Christopher Columbus Flagship, the Santa María, runs aground on Christmas Day 1492, on a reef off the northwest coast of what is now Haiti but the exact location remains a mystery. The ship was declared a total loss, and its timbers were salvaged to build the Fort which he named "La Navidad", the first European settlement in the New World, where 39 members of Columbus's crew were left behind.
Columbus left for Spain in January of 1493, with the other two ships, the Niña and the Pinta. Columbus returned to the settlement a year later to find it destroyed, the fort in ruins and his men gone.It is believed the Taíno people had retaliated against the European mistreatment and violence, killing the men and burning the fort.